Table III.

COX-2, PRDXI, PRDX6 and NF-κB mRNA expression level of OSCC tissues according to stage.

	OSCC mRNA expression, pg/ml
Genes	Low-stage tumor (T1) (n=9)	High-stage tumor (T3 and T4) (n=28)	P-value
COX-2	5.240±1.586	12.511±2.778	0.147
PRDXI	5.234±3.078	13.981±2.509	0.047
PRDX6	2.290±0.771	3.872±0.752	0.288
NF-κB	2.373±0.965	10.970±4.115	0.147

Low stage: tumor size ≤2 cm (T1), high stage: tumor size >4 cm, invasion of adjacent structures (T3, 4). OSCC, oral squamous cell carcinoma; COX-2, cyclooxygenase 2; PRDX, peroxiredoxin; NF-κB, nuclear factor-κB.