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. 2015 Sep 16;10(5):3129–3136. doi: 10.3892/ol.2015.3705

Table IV.

COX-2, PRDXI, PRDX6 and NF-κB mRNA expression level of OSCC tissues according to differentiation.

OSCC mRNA expression, pg/ml

Genes Low-grade tumor (G1) (n=39) High-grade tumor (G2 and G3) (n=11) P-value
COX-2 7.245±2.482 10.469±6.887 0.788
PRDXI 9.848±1.907 15.368±3.591 0.171
PRDX6 3.036±0.532 4.378±1.371 0.343
NF-κB 8.488±1.490 17.218±5.228 0.048

Low-grade tumor, well-differentiated (G1); high-grade tumor, moderately-differentiated (G2) and poorly-differentiated (G3). OSCC, oral squamous cell carcinoma; COX-2, cyclooxygenase 2; PRDX, peroxiredoxin; NF-κB, nuclear factor-κB.