Table V.
Incidences of liver and bile duct tumors induced by BOP.
Animals with tumors, n (%) | |||||
---|---|---|---|---|---|
Cholangiocellular tumors | |||||
Group | Treatment (no. of animals examined) | Hepatocellular adenoma | Adenoma | Adenocarcinoma | Total |
1 | BOP (34) | 2 (6) | 1 (3) | 0 (0) | 1 (3) |
2 | BOP+5% FBRA (30) | 1 (3) | 0 (0) | 0 (0) | 0 (0) |
3 | BOP+10% FBRA (29) | 0 (0) | 0 (0) | 1 (3) | 1 (3) |
4 | BOP→5% FBRA (30) | 1 (3) | 1 (3) | 1 (3) | 2 (7) |
5 | BOP→10% FBRA (29) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
BOP, N-nitrosobis(2-oxopropyl)amine; FBRA, fermented brown rice by Aspergillus oryzae.