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. 2015 Oct 16;10(6):3377–3384. doi: 10.3892/ol.2015.3809

Table V.

Incidences of liver and bile duct tumors induced by BOP.

Animals with tumors, n (%)

Cholangiocellular tumors

Group Treatment (no. of animals examined) Hepatocellular adenoma Adenoma Adenocarcinoma Total
1 BOP (34) 2 (6) 1 (3) 0 (0) 1 (3)
2 BOP+5% FBRA (30) 1 (3) 0 (0) 0 (0) 0 (0)
3 BOP+10% FBRA (29) 0 (0) 0 (0) 1 (3) 1 (3)
4 BOP→5% FBRA (30) 1 (3) 1 (3) 1 (3) 2 (7)
5 BOP→10% FBRA (29) 0 (0) 0 (0) 0 (0) 0 (0)

BOP, N-nitrosobis(2-oxopropyl)amine; FBRA, fermented brown rice by Aspergillus oryzae.