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. 2015 Sep 17;10(5):2802–2806. doi: 10.3892/ol.2015.3719

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — GA inhibits tumor growth in an NCI-H1993 xenograft model. (A) Nude mice bearing NCI-H1993 tumors received once daily i.p. injections with GA at the indicated dose, vehicle or positive control for up to 3 weeks. Tumor volume was measured using calipers on the indicated days. (B) NCI-H1993 tumors resected from nude mice on day 21 of the efficacy study. (C) Body weight changes during the efficacy study. Each dose of GA demonstrated no toxicity to the NCI-H1993 xenograft model. Values are expressed as the mean ± SD, n=10. *P<0.05 vs. vehicle group; **P<0.01 vs. vehicle group. GA, gambogic acid; i.p., intraperitoneal; i.v., intravenous; SD, standard deviation.