Table III.
Clinical characteristics of AA patients with normal and heterozygous PTPN22 genotype.
| Characteristics | CC genotype (n=59) | CT genotype (n=5) | P-value |
|---|---|---|---|
| Age range, years | 3–73 | 7–23 | |
| Mean age, years | 32.15±15.39 | 14.00±5.83 | 0.0003a |
| Immune diseases | 12/59 | 0/5 | 0.6016 |
| DM | 30/59 | 0/5 | 0.0853 |
| AH | 19/59 | 0/5 | 0.3156 |
| Vitiligo | 3/59 | 0/5 | 0.5583 |
| Alopecia | 3/59 | 0/5 | 0.5583 |
| Positive family history | 41/59 | 2/5 | 0.3939 |
a
P<0.05 indicates a statistically significant difference. Data are presented as a range, mean ± standard deviation or number/total number. AA, alopecia areata; PTPN22, protein tyrosine phosphatase, non-receptor type 22; DM, diabetes mellitus; AH, arterial hypertension.