Figure 3. teHSP90 maintains activity of BCR proteins in ABC DLBCLs.

HBL-1, TMD8, and OCI-Ly10 cells were exposed to vehicle or PU-H71 (1 μM) for increasing times as indicated. Lysates were subjected to immunoblotting with the indicated antibodies. β-Actin was used as a loading control. The relative abundance of each phosphorylated protein relative to each total protein was quantified by densitometry for each timepoint and is shown on the line graphs. Dotted lines, phospho. The relative abundance of each total protein relative to actin was quantified by densitometry for each timepoint and is shown in the line graphs. Solid lines, total.