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. 2015 Nov 3;125(12):4572–4586. doi: 10.1172/JCI82045

Figure 7. DLL4 is necessary for efficient LEC migration.

Figure 7

(A) Individual LEC migration was tracked for 20 hours after a wound was made in a LEC monolayer transfected with either control or DLL4-specific siRNA and treated with BSA or VEGFC. Tracks in red or black represent LECs that traveled less than or more than the average actual distance (avg. dist.), respectively. Data shown are representative of 3 independent experiments. (B) Total LEC track distance (mean ± SD) in arbitrary units (a.u.); n = 3. (C) Actual LEC distance (mean ± SD) traveled in arbitrary units; n = 3. (D) Directionality (actual/total distance; mean ± SD); n = 3. *P < 0.05, **P < 0.01, 2-tailed unpaired Student’s t test.