Table 2.
Genotype and allele frequencies distribution of IL-23R polymorphisms between controls and cases
| dbSNP ID/CNV | Genotype/Allele | Controls n (%) | PTB cases n (%) | OR (95 % CI) |
|---|---|---|---|---|
| rs1884444 | TT | 82 (33.1) | 87 (34.8) | 1 |
| GT | 122 (49.2) | 114 (45.6) | 0.88 (0.59–1.31) | |
| GG | 44 (17.7) | 49 (19.6) | 1.05 (0.63–1.74) | |
| T | 286 (57.7) | 288 (57.6) | 1 | |
| G | 210 (42.3) | 212 (42.4) | 1.00 (0.78–1.29) | |
| rs10889664 | CC | 93 (37.5) | 103 (41.2) | 1 |
| CT | 117 (47.2) | 109 (43.6) | 0.84 (0.57–1.23) | |
| TT | 38 (15.3) | 38 (15.2) | 0.90 (0.53–1.53) | |
| C | 303 (61.1) | 315 (63.0) | 1 | |
| T | 193 (38.9) | 185 (37.0) | 0.92 (0.71–1.19) | |
| rs11465788 | TT | 85 (34.7) | 87 (34.9) | 1 |
| CT | 120 (49.0) | 114 (45.8) | 0.93 (0.63–1.38) | |
| CC | 40 (16.3) | 48 (19.3) | 1.17 (0.70–1.96) | |
| T | 290 (59.2) | 288 (57.8) | 1 | |
| C | 200 (40.8) | 210 (42.2) | 1.06 (0.82–1.36) | |
| rs7518660 | GG | 105 (42.3) | 33 (13.2) | 1 |
| AG | 116 (46.8) | 109 (43.6) | 2.99 (1.87–4.79) | |
| AA | 27 (10.9) | 108 (43.2) | 12.73 (7.16–22.6) | |
| G | 326 (65.7) | 175 (35.0) | 1 | |
| A | 170 (34.3) | 325 (65.0) | 3.56 (2.74–4.62) | |
| rs11465802 | CC | 74 (30.0) | 70 (28.0) | 1 |
| AC | 121 (49.0) | 121 (48.4) | 1.06 (0.70–1.60) | |
| AA | 52 (21.0) | 59 (23.6) | 1.20 (0.73–1.97) | |
| C | 269 (54.5) | 261 (52.2) | 1 | |
| A | 225 (45.5) | 239 (47.8) | 1.10 (0.85–1.41) | |
| rs10889677 | AA | 76 (30.9) | 57 (22.9) | 1 |
| AC | 119 (48.4) | 121 (48.6) | 1.36 (0.89–2.08) | |
| CC | 51 (20.7) | 71 (28.5) | 1.85 (1.13–3.05) | |
| A | 271 (55.1) | 235 (47.2) | 1 | |
| C | 221 (44.9) | 263 (52.8) | 1.37 (1.07–1.76) | |
| CNV | CN < 2 | 3 (1.2) | 7 (2.8) | 2.66 (0.68–10.41) |
| CN = 2 | 230 (92.0) | 202 (80.8) | 1 | |
| CN > 2 | 17 (6.8) | 41 (16.4) | 2.75 (1.51–4.98) |
PTB pulmonary tuberculosis, OR odds ratio, CI confidence interval, CNV copy number variation, CN copy number