Table IV.
Comparison between the patients who developed POCD one day after surgery and the patients without POCD.
| Characteristic | No POCD | POCD | P-value |
|---|---|---|---|
| N | 72 | 28 | – |
| Gender n/N (% female) | 33/72 (46) | 13/28 (46) | 0.830 |
| Age, years | 69±5 | 69±6 | 0.770 |
| ASA group, n/N (%) | 0.208 | ||
| Group I | 33/72 (46) | 10/28 (36) | – |
| Group II | 31/72 (43) | 11/28 (39) | – |
| Group III | 8/72 (11) | 7/28 (25) | – |
| Weight, kg | 62±7 | 61±8 | 0.342 |
| Height, cm | 164±7 | 163±6 | 0.667 |
| BMI, kg/m2 | 23.3±3.1 | 22.8±3.7 | 0.538 |
| Disease duration, years | 2.5 (2–3.5) | 3.5 (2.5–4) | 0.009 |
| No. of co-morbid diseases | 1 (1–2) | 2 (1–2) | 0.017 |
| No. of medication at home | 2 (1–3) | 2 (1–3) | 0.544 |
| Surgical duration, min | 61±9 | 60±10 | 0.699 |
| Anesthesia duration, min | 78±10 | 78±9 | 0.866 |
| 6% hydroxyethyl starch, ml | 87±17 | 91±12 | 0.227 |
| Ringer's lactate, ml | 555±65 | 568±62 | 0.364 |
| IL-1β, ng/l | 7.8±1.6 | 8.9±1.9 | 0.013 |
| IL-6, ng/l | 69.0±11.6 | 77.7±16.5 | 0.015 |
| CRP, mg/dl | 7.1±1.1 | 8.1±1.8 | 0.010 |
| Baseline MMSE | 28.4±1.6 | 28.2±1.6 | 0.626 |
Data are presented as mean ± standard deviation or mean (interquartile range). n/N is number with charareristic/total number. DEX, dexmedetomidine; POCD, postoperative cognitive dysfunction; BMI, body mass index; IL, interleukin; CRP, C-reactive protein; MMSE, Mini Mental-State Examination; ASA, American Society of Anesthesiologist physical status classification system, range 1 (normal health) to 5 (moribund).