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. 2015 Dec 1;15:943. doi: 10.1186/s12885-015-1948-8

Fig. 1.

Fig. 1

Examples of ROCKII S1366 phosphorylation immunohistochemical staining in breast carcinomas. Breast carcinoma cases varied greatly in ROCKII S1366 phosphorylation. a, dA grade-2 invasive ductal carcinoma with negative signal; (b, e) a metastatic ductal carcinoma in axillary lymph node showing significant positive signal in nuclei; (c, f) a grade-2 invasive ductal carcinoma with cytosol and nuclear positive signal. D-F shows enlargements of the boxed regions in A-C. Scale bars, 20 μm