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. 2015 Sep 23;10(5):1750–1758. doi: 10.3892/etm.2015.2766

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Copyright: © Xiao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Treatment with the antioxidant Tempol improves cardiac function in type 1 diabetic mice. (A) Quantitative analysis of body weight (upper panel) and whole blood glucose concentration (lower panel) in control (CON), diabetic (DM) and DM + Tempol groups (n=5). (B) Representative transmittal Doppler flow profile of the CON and DM groups at 18 weeks. (C) Quantitative analysis of heart rate (HR), E-wave velocity (MVE), mitral valve area (MVA), E- to A-wave ratio (E/A), E-wave detection time (DT), E-wave deceleration rate (EWDR), isovolumetric relaxation time (IVRT), and ejection time (ET) of the CON and DM groups at the 7-, 10-, 14- and 18-week time-points (n=5). Values are presented as the mean ± standard error of the mean. *P≤0.05 vs. the CON group; ^#P≤0.05 vs. the DM group.