Table 3.

Univariate analysis of the DFS and OS in 195 colon cancer patients

Variable	DFS			OS
	HR	95 % CI	p	HR	95 % CI	p
Age (years)
< 65
> 65	0.958	0.581–1.547	0.832	1.048	0.581–1.888	0.877
Sex
male
female	0.959	0.593–1.552	0.865	1.227	0.681–2.212	0.496
Location
right
others	1.143	0.957–1.365	0.139	1.159	0.936–1.436	0.176
AJCC stage
I + II
III + IV	3.248	2.256–4.675	<0.001*	15.219	4.281–54.102	<0.001*
T stage
T1 + T2
T3 + T4	1.638	1.160–2.313	0.005*	1.226	0.846–1.777	0.282
N stage
N0
N1 + N2	3.293	2.413–4.494	<0.001*	2.569	1.773–3.724	<0.001*
M stage
M0
M1	5.641	2.661–11.958	<0.001*	8.713	3.786–20.055	<0.001*
Differentiation
Well + moderate
Poor	1.404	1.010–1.952	0.043	1.363	0.915–2.032	0.128
Vascular invasion
no
Yes	4.356	2.266–8.35	<0.001*	3.705	1.646–8.337	0.002*
Ki–67 expression
low
high	1.311	0.952–1.084	0.097	0.924	0.659–1.295	0.646
KPNA2 expression
low
high	1.969	1.410–2.748	<0.001*	1.729	1.158–2.583	0.007*

HR hazard ratio, CI confidence interval. *p < 0.005 indicates that the lower limit of the 95 % CI of HR is >1