Table II.
Comparison of clinical outcomes of patients with polycystic ovarian syndrome treated with two protocols.
| Variables | Ultra-long protocol (n=75) | Long protocol (n=72) | P-value |
|---|---|---|---|
| LH level on the day prior to Gn (mIU/ml) | 0.63±0.69 | 1.89±0.87 | <0.0001a |
| Dosage of Gn (IU) | 2104.9±908.92 | 2020.76±899.76 | 0.5737 |
| Duration of Gn (days) | 11.52±2.15 | 11.85±2.13 | 0.3562 |
| P level on hCG day (ng/ml) | 0.63±0.22 | 0.77±0.23 | 0.0002a |
| E2 level on hCG day (pg/ml) | 3707.29±1307.97 | 3667.29±1621.14 | 0.8698 |
| Px1,000/E2 on HCG day | 0.19±0.08 | 0.25±0.13 | 0.0006a |
| LH level on HCG day (mIUml) | 1.40±0.45 | 1.29±0.51 | 0.1558 |
| Mean number of oocytes retrieved | 14.63±5.96 | 15.58±5.00 | 0.2928 |
| Fertilization rate (%) | 84.11±17.16 | 82.26±14.95 | 0.4865 |
| Good quality embryo rate (%) | 71.13±25.10 | 66.52±25.15 | 0.2679 |
| Implantation rate (%) | 59.56 (81/136) | 44.09 (56/127) | 0.012a |
| Cancel rate (%) | 9.33 (7/75) | 13.89 (10/72) | 0.388 |
| Number of transferred embryos | 2.0±0 | 2.05±0.28 | 0.1595 |
| Clinical pregnancy rate per transfer (%) | 77.94 (53/68) | 61.29 (38/62) | 0.039a |
| Severe OHSS rate (%) | 1.33 (1/75) | 2.78 (2/72) | 0.536 |
| Abortion rate (%) | 4.76 (3/53) | 4.76 (2/38) | 1.000 |
| Ectopic pregnancy rate (%) | 0 (0/53) | 2.38 (1/38) | 0.218 |
LH, lutenizing hormone; Gn, gonadotropin; P, progestogen; E2, estrogen; hCG, human chorionic gonadotophin; OHSS, ovarian hyperstimulation syndrome.
a
P<0.05.