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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Eur J Med Chem. 2014 Sep 8;86:714–723. doi: 10.1016/j.ejmech.2014.09.023

Fig. 3.

Fig. 3

Incubation assay to determine binding kinetics of compound 6g. IC50 without incubation: 0.44 ± 0.03 µM, IC50 after 3 min incubation: 0.42 ± 0.05 µM, IC50 after 20 min incubation: 0.38µ ± 0.03 µM, IC50 after 60 min incubation: 0.21 ± 0.06 µM.