Table 3.
Point scoring system of predictive factors and median overall survival by risk zones
| Prognostic factor | Multivariable analysis hazard ratio (95 % CI) | Point score | |
|---|---|---|---|
| KPS | |||
| >80 | 1.00 | 0 | |
| ≤80 | 8.09 (3.79-17.28) | 4 | |
| Extracranial disease | |||
| absent | 1.00 | 0 | |
| active/stable | 5.37 (1.65-17.48) | 3 | |
| No. of lesions | |||
| 1 | 1.00 | 0 | |
| 2-4 | 2.61 (1.37-4.96) | 1.5 | |
| >4 | 3.24 (1.56-6.72) | 2 | |
| Gender | |||
| Female | 1.00 | 0 | |
| Male | 1.76 (1.04-2.97) | 1 | |
| Risk zone | Point ranges | No. of patients (%) | Median OS, mo (95 % CI) |
| Low | 0-3 | 15 (17.4) | not reached |
| Moderate | 4-6 | 61 (71.7) | 7.60 (3.73-11.47) |
| High | 6.5-10 | 10 (11.6) | 2.40 (1.79-3.01) |
Abbreviations: CI 95 % confidence interval, KPS Karnofsky performance status, OS overall survival