Table 5.
Point scoring system of predictive factors and median time to distant failure by risk zones
| Prognostic factor | Multivariable analysis hazard ratio (95 % CI) | Point score | |
|---|---|---|---|
| KPS | |||
| >80 | 1.00 | 0 | |
| ≤80 | 4.37 (1.58-12.06) | 2 | |
| Extracranial disease | |||
| absent | 1.00 | 0 | |
| active/stable | 2.60 (1.29-5.27) | 1 | |
| No. of lesions | |||
| 1 | 1.00 | 0 | |
| 2-3 | 2.30 (1.08-4.91) | 1 | |
| >3 | 5.27 (2.40-11.57) | 2 | |
| Risk zone | Point ranges | No. of patients (%) | Median time to DF, mo (95 % CI) |
| Low | 0 | 8 (9.3) | not reached |
| Moderate | 1-2 | 46 (53.4) | 4.80 (3.87-5.73) |
| High | 3-5 | 23 (26.7) | 2.00 (1.50-2.50) |
Abbreviations: CI 95 % confidence interval, KPS Karnofsky performance status, DF distant failure