Table 3.

Effectiveness rates and RRs between combination therapies and three monotherapies as found in literature

	No. of TBs	Effective TBs	Effective rate (%)	Effective 95 % CI (%)	RR between combination therapies and others
On combination therapies (pooled)	437	264	60.4	55.8–65.0	–
On DPA monotherapy [15]	99	73	73.7	65.1–82.4	0.82
On TETA monotherapy [37]	109	90	82.6	75.4–89.7	0.73
On zinc monotherapy [16]	88	63	71.6	62.2–81.0	0.84

TBs treatment blocks, CI confidence interval, RR relative risk ratio, DPA penicillamine, TETA trientine