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. 2015 Oct 25;43(21):10292–10307. doi: 10.1093/nar/gkv1089

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Length distribution of assembled AluYa5 and AluYb8 insertions. (A) Scaled representation of the AluYa5 and AluYb8 consensus and element properties. The Alu is comprised of two arms (left, blue; right, grey) joined by an A-rich region and having a 3′ poly-A tail. The A and B boxes indicate promoter regions. A 31 bp insertion distinguishes the arms. AluYb8 has a 3′ 7 bp insertion relative to Ya5; the sequences are otherwise structurally conserved. The gold bar shows bases within SRP/14 binding sites. (B) The size distribution of 351 AluYa5 and 215 AluYb8 assembled insertions relative to the respective subfamily consensus. The red dashed lines indicate peaks in truncation near 45 bp and 170 bp. The number of assembled insertions containing an aligned nucleotide is shown against the corresponding position in the consensus.