Figure 4.

4mC-containing motif characterizations and distributions in C. kristjanssonii. (A) Motif sequence profile and sequence conservation analysis. Methylated cytosine is indicated with 4m. (B) Motif distributions in reference genome, untreated- and Tet-treated samples. (C) Single cytosine methylation level distributions of each motif in the untreated sample. (D) Single cytosine methylation level distributions of each motif in the Tet-treated sample. The levels in both samples were scaled by 4mC conversion rate generated from 76-mer probes (Supplementary Figure S2).