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Schematic representation of the catalytic role of EF-G loop II in ribosome recycling. At the end of translation, RRF binds to PoTC inducing the conformational change of H69 and h44 to destabilize B2a. Upon EF-G•GTP binding, loop II (blue) locates in the vicinity of B2a. Together with RRF, loop II disassembles the ribosome into the subunits.
