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. 2015 Dec 1;9(12):e0004259. doi: 10.1371/journal.pntd.0004259

Fig 7. Inhibitors of CCHFV entry and transcription inhibit tecVLP signal production.

Fig 7

(A) Neutralization assays of tecVLPs treated with mAbs. Percent inhibition was calculated by comparing the NanoLuc signal strength in SW-13 cells treated with tecVLP and mAbs to signal in cells treated with tecVLPs and a control mAb. (B) Percent inhibition (compared to untreated tecVLP) in SW-13 cells treated with tecVLPs and indicated inhibitors (top panel), and 50% effective concentration (EC50), 50% cytotoxicity concentration (CC50), and selectivity index (SI) for ribavirin and chloroquine in these cells (bottom panel, average of 3 experiments).