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. 2015 Dec 1;9(12):e0004256. doi: 10.1371/journal.pntd.0004256

Table 4. Adjusted prevalence ratios for single and combined deworming and household finished floor and relative excess risk due to interaction.

Ascaris Hookworm Trichuris
Deworming Finished floor n/N aPR c (95% CI) n/N aPR c (95% CI) n/N aPR c (95% CI)
- - 141/847 (ref) 55/847 (ref) 177/847 (ref)
+ - 59/572 0.53 (0.39,0.71) 31/572 0.93 (0.60,1.44) 126/572 0.91 (0.75,1.11)
- + 9/110 0.60 (0.32,1.15) 3/110 0.54 (0.16,1.87) 23/110 1.12 (0.75,1.67)
+ + 4/93 0.28 (0.11,0.75) 1/93 0.27 (0.04,2.07) 16/93 0.85 (0.54,1.33)
RERI b 0.56 (-3.64,2.40) -1.14 (—,—) d -0.18 (-1.48,0.37)

aPRs adjusted for age, sex, household floor type, geographic district, household wealth, cluster-level wealth, and mother’s education level.

bRelative excess risk due to interaction (RERI). A RERI = 0 indicates no interaction on the additive scale, RERI>0 indicates synergistic interaction on the additive scale for monotonic aPRs, RERI>1 indicating synergistic interaction on the additive scale for non-monotonic aPRs, and RERI<0 indicates antagonistic interaction on the additive scale.

cPRs adjusted for age, sex, hygienic latrine access, geographic district, household wealth, cluster-level wealth, and mother’s education level

d95% Confidence intervals were not estimated because there were strata with fewer than 5 observations for this measure.