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. 2015 Nov 27;71(Pt 12):1531–1539. doi: 10.1107/S2053230X15022049

Table 1. Inhibition of P. falciparum PMII, PMI and PMIV and human cathepsin D by the studied inhibitors (Jaudzems et al., 2014).

    IC50M)
Compound Formula PMII PMI PMIV Cathepsin D
PG418 graphic file with name f-71-01531-scheme1.jpg 0.070 0.30 0.024 0.042
PG394 graphic file with name f-71-01531-scheme2.jpg 0.8 4.1 0.25 0.35
NU655 graphic file with name f-71-01531-scheme3.jpg 0.15 0.70 0.029 0.043