Table 1. Inhibition of P. falciparum PMII, PMI and PMIV and human cathepsin D by the studied inhibitors (Jaudzems et al., 2014 ▸).
IC50 (µM) | |||||
---|---|---|---|---|---|
Compound | Formula | PMII | PMI | PMIV | Cathepsin D |
PG418 | 0.070 | 0.30 | 0.024 | 0.042 | |
PG394 | 0.8 | 4.1 | 0.25 | 0.35 | |
NU655 | 0.15 | 0.70 | 0.029 | 0.043 |