TABLE 2.
Best Response to Treatment with Obatoclax Plus Docetaxel (Phase 2)
| Obatoclax 60 mg × 2 days + Docetaxel 75 mg/m2
|
|||
|---|---|---|---|
| Stage 1a n = 11 | Stage 2 n = 16 | Total N = 27 | |
| Best response, n (%) | |||
| Complete response | 0 | 0 | 0 |
| Partial response | 1 (9.1) | 2 (12.5) | 3 (11.1) |
| Stable disease ≥12 weeks | 1 (9.1) | 1 (6.3) | 2 (7.4) |
| Stable disease <12 weeks | 2 (18.2) | 5 (31.3) | 7 (25.9) |
| Progressive disease | 7 (63.6) | 8 (50.0) | 15 (55.6) |
| Overall response, n (%) | 1 (9.1) | 2 (12.5) | 3 (11.1) |
a
Includes one phase 1 patient with partial response.