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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Nano Today. 2015 Sep 5;10(4):487–510. doi: 10.1016/j.nantod.2015.06.006

Figure 4.

Figure 4

Phagocytic-particle recognition is responsible for nanoparticle clearance and internalization. Macrophage surface receptors are depicted here that could be responsible for nanoparticle recognition. Each receptor that recognizes the nanoparticle will induce a specific internalization mechanism, outlined in the diagram. Downstream inflammatory effects, triggered by receptor engagement, can be induced via these internalization pathways.