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. 2015 Dec 1;10(12):e0143971. doi: 10.1371/journal.pone.0143971

Table 4. Cut-off values for diagnosing severe sepsis/septic shock with CLEIA or quantitative ICT.

AUC Cut-off value Sensitivity Specificity Accuracy PPV NPV LR+ LR− 95% CI
CLEIA 0.912 865.0 pg/dL 86.4% 91.2% 90.0% 76.0% 95.4% 9.79 0.15 0.847 to 0.978
ICT 0.881 762.7 pg/dL 85.7% 87.9% 87.4% 69.2% 95.1% 7.07 0.16 0.787 to 0.975

CI: confidence interval; CLEIA: chemiluminescent enzyme immunoassay; ICT: immunochromatographic test; LR: likelihood ratio; NPV: negative predictive value; PPV: positive predictive value.