Table 4. Cut-off values for diagnosing severe sepsis/septic shock with CLEIA or quantitative ICT.
AUC | Cut-off value | Sensitivity | Specificity | Accuracy | PPV | NPV | LR+ | LR− | 95% CI | |
---|---|---|---|---|---|---|---|---|---|---|
CLEIA | 0.912 | 865.0 pg/dL | 86.4% | 91.2% | 90.0% | 76.0% | 95.4% | 9.79 | 0.15 | 0.847 to 0.978 |
ICT | 0.881 | 762.7 pg/dL | 85.7% | 87.9% | 87.4% | 69.2% | 95.1% | 7.07 | 0.16 | 0.787 to 0.975 |
CI: confidence interval; CLEIA: chemiluminescent enzyme immunoassay; ICT: immunochromatographic test; LR: likelihood ratio; NPV: negative predictive value; PPV: positive predictive value.