Table 1. Correlation between demography and histopathology with recurrence.
Variable | No recurrence (n = 452) | Recurrence (n = 50) | P value | ||
---|---|---|---|---|---|
Age (median and range) | 39 (21–71) | 38 (21–62) | 0.844 a | ||
Menopause | 0.783 b | ||||
Yes | 23 (5.1%) | 3 (6%) | |||
No | 429 (94.9%) | 47 (94%) | |||
Parity (median and range) | 1 (0–3) | 1 (0–3) | >0.99 a | ||
Conization method | 0.454 b | ||||
LEEP | 148 (32.7%) | 19 (38%) | |||
CKC | 304 (67.3%) | 31 (62%) | |||
Cone depth (mm) | 0.049 b | ||||
≤18 | 162 (35.8%) | 25 (50%) | |||
>18 | 290 (64.2%) | 25 (50%) | |||
Punch biopsy | 0.325 b | ||||
CIN1 | 29 (6.4%) | 3 (6%) | |||
CIN2 | 154 (34.1%) | 12 (24%) | |||
CIN3 | 269 (59.5%) | 35 (70%) | |||
High risk HPV | 0.289 b | ||||
Yes | 412(91.2%) | 48 (96%) | |||
No | 40 (8.8%) | 2(4%) | |||
Colposcopy adequacy | 0.227 b | ||||
Yes | 354 (78.3%) | 35 (70%) | |||
No | 98 (21.7%) | 15 (30%) | |||
Cone pathology | 0.271 b | ||||
Normal | 54 (11.9%) | 3 (6%) | |||
CIN1 | 67(14.8%) | 6 (12%) | |||
CIN2 | 105(23.2%) | 9 (18%) | |||
CIN3 | 226 (50%) | 32 (64%) | |||
Surgical margins | <0.001 b | ||||
Negative | 402 (97.1%) | 38 (82.6%) | |||
Positive | 12 (2.9%) | 8 (17.4%) | |||
Follow-up (months, median, range) | 34 (12–94) | 12 (1–55) |
a Pearson Chi-square test.
b Mann-Whitney U test.