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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: J Glob Antimicrob Resist. 2015 Jun 3;3(3):174–183. doi: 10.1016/j.jgar.2015.04.006

Fig. 3.

Fig. 3

Distance between resistance change signature vectors of two bacteria/antimicrobial pairs (BAPs) compared with Escherichia coli & carbapenems. (A) Shows the close similarity between Enterococcus faecalis & vancomycin and E. coli & carbapenems compared with Pseudomonas aeruginosa & fluoroquinolones. For each BAP, the resistance change signature vectors represent the changes in resistance between years ordered according to their topological sequence. At each point of topological order, the distance between the signature vectors of the two pairs relative to E. coli & carbapenems is shown. The horizontal axis represents the signature vectors of E. coli & carbapenems. The bars represent the distance relative to E. coli & carbapenems of signature vectors of E. faecalis & vancomycin (black) or P. aeruginosa & fluoroquinolones (grey). (B) Dendrogram representing the results of (A) on a relative similarity scale.