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. Author manuscript; available in PMC: 2016 Jul 17.
Published in final edited form as: ACS Chem Biol. 2015 May 7;10(7):1667–1675. doi: 10.1021/acschembio.5b00109

Table 2.

Effects of multiple β3 to cyclic β residue modification of Bim-derived α/β-peptides on binding to anti-apoptotic proteins.

graphic file with name nihms-718320-f0010.jpg
a

Ki values obtained from competition fluorescence polarization measurements (experimental uncertainty ~2-fold). Cyclic β residues U, X and Z are defined in Figure 3.