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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Pain Symptom Manage. 2015 Aug 19;50(6):758–767. doi: 10.1016/j.jpainsymman.2015.07.005

Table 2.

Multivariate Analysis of Main Outcomes at 12 weeks, Controlling for Baseline

Outcome Usual Care Intervention P Value
N x̄±SD x̄a N x̄±SD x̄a Mainb Interc
FACT-L (Range = 0–140; higher = better QOL) Early 102 93.7±20.6 97.7 129 115.4±12.6 112.5 <.001 <.001
Late 91 105.3±20.1 105.2 135 105.8±18.8 105.7
Total 193 99.2±21.1 101.4 264 110.5±16.8 109.1
Lung Cancer Subscaled (Range = 0–32; higher = better QOL) Early 105 22.2±4.8 23.1 129 27.1±3.4 26.2 <.001 .003
Late 106 24.7±5.1 24.8 135 25.2±4.6 25.4
Total 211 23.4±5.1 23.9 264 26.2±4.2 25.8
Trial Outcome Index (Range =0–136; higher = better QOL) Early 105 56.3±13.1 58.4 129 70.0±8.4 67.8 <.001 <.001
Late 106 63.4±14.0 63.5 135 64.1±12.2 64.5
Total 211 59.9±14.0 60.1 264 67.0±10.9 66.2
Physical Well Beingd (Range = 0–28; higher = better QOL) Early 105 19.5±6.2 20.2 129 23.3±3.3 22.4 <.001 .004
Late 106 21.2±6.2 21.4 135 22.2±4.9 22.4
Total 211 20.3±6.2 20.8 264 22.8±4.2 22.4
Social/Family Well Beingd (Range = 0–28; higher = better QOL) Early 105 20.4±6.9 21.9 129 24.5±5.0 24.1 .49 <.001
Late 105 24.1±4.3 23.8 135 22.7±6.5 22.2
Total 211 22.3±6.0 22.9 264 23.6±5.8 23.1
Emotional Well Beingd (Range = 0–24; higher = better QOL) Early 105 16.7±4.8 17.2 129 20.8±3.5 20.7 <.001 <.001
Late 106 18.5±4.9 18.3 135 19.0±3.9 18.9
Total 211 17.6±4.9 17.7 264 19.9±3.8 19.8
Functional Well Beingd (Range = 0–28; higher = better QOL) Early 105 14.6±4.9 15.4 129 19.5±3.5 19.1 <.001 <.001
Late 106 17.5±5.4 17.2 135 16.6±6.0 16.5
Total 211 16.1±5.4 16.3 264 18.0±5.1 17.8
FACIT-Sp-12 (Range = 0–48; higher = better spiritual well-being) Early 105 33.4±9.5 35.5 129 40.3±7.5 39.1 .001 .001
Late 106 37.3±8.9 37.2 135 37.5±9.7 37.1
Total 211 35.4±9.3 36.3 264 38.9±8.8 38.1
Meaning (Range = 0–32; higher = better spiritual well-being) Early 105 24.0±5.9 24.8 129 29.3±3.5 28.3 <.001 <.001
Late 106 25.5±6.1 25.8 135 25.7±6.3 25.9
Total 211 24.7±6.0 25.3 264 27.5±5.4 25.8
Psychological Distress (Range = 0–10; higher = more distress) Early 102 3.5±2.8 3.5 129 1.8±1.9 1.7 <.001 .001
Late 91 3.0±2.5 3.1 135 2.6±2.4 2.7
Total 193 3.2±2.7 3.3 264 2.2±2.2 2.2
a

Adjusted means

b

Main effect of group

c

Interaction between group and stage

d

Pillai’s Trace Multivariate p value of < .001 for group and for group by stage interaction