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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Pain. 2015 Sep 3;16(12):1268–1279. doi: 10.1016/j.jpain.2015.08.009

Table 2.

Experimental pain response following TENS, by session

Session 1
Mean Δ (95%CI)
p Session 2
Mean Δ (95%CI)
p Session 3
Mean Δ (95%CI)
p Session 4
Mean Δ (95%CI)
p
PPT Young 0.46 (0.08,0.84) 0.34 (−0.05,0.74) 0.21 (−0.14,0.56) 0.19 (−0.19,0.57)
Middle 0.19 (−0.19,0.57) 0.436 0.14 (−0.22,0.50) 0.362 0.08 (−0.27,0.42) 0.588 0.20 (−0.16,0.56) 0.028*
Older 0.52 (0.14,0.90) 0.51 (0.15,0.87) 0.32 (−0.01,0.66) 0.82 (0.45,1.20)
Total 0.39 (0.17,0.61) 0.001 0.33 (0.12,0.55) 0.003 0.20 (0.01,0.40) 0.044 0.41 (0.19,0.62) <0.001

TS Young 4.76 (−3.99,13.52) −2.77 (−11.30,5.77) 0.17 (−6.80,7.14) 0.13 (−5.57,5.82)
Middle 6.44 (−2.10,14.95) 0.571 0.32 (−7.75,8.38) 0.870 −3.35 (−3.82,10.52) 0.463 −3.74 (−8.97,1.49) 0.556
Older 0.45 (−7.62,8.52) −0.94 (−9.23,7.34) −2.79 (−3.99,9.57) 0.83 (−4.54,6.21)
Total 3.89 (−0.99,8.76) 0.116 −1.13 (−5.92,3.66) 0.638 −0.13 (−4.16,3.90) 0.948 −0.93 (−4.07,2.21) 0.427

AS Young −27.14 (−0.96,−53.32) −33.12 (−6.58,−59.66) −14.97 (0.26,−30.20) −8.81 (7.94,−25.56)
Middle −29.70 (−4.86,−54.54) 0.925 −39.73 (−15.26,−64.19) 0.600 −7.08 (8.15,−22.31) 0.562 0.58 (16.88,−15.72) 0.112
Older −34.20 (−9.31,−58.99) −22.35 (−4.86,−54.54) −3.93 (18.37,−10.52) −24.14 (−7.39,−40.88)
Total −30.33 (−15.73,−44.93) <0.001 −31.73 (−17.20,−46.27) <0.001 −8.66 (−0.02,−17.31) 0.049 −10.78 (−1.21,−20.37) 0.028

Mean Δ, mean change after TENS (95% CI of change reported in parentheses); p Age groups, significance value of age by time interaction; p Total, significance of time main effect (before and after TENS);

*

PPT change in older group only.