Table 1.
Summary of included studies
| Author | Abrams | Ellis | Ware | Wilsey | Wilsey |
|---|---|---|---|---|---|
| Year | 2007 | 2008 | 2010 | 2008 | 2013 |
| Neuropathy | HIV-DSPN | HIV-DSPN | post- traumatic |
sensory | mixed |
| Subjects | 50 | 34 | 23 | 38 | 39 |
| Allocation | randomized | ||||
| Intervention | Inhaled cannabis versus placebo | ||||
| Outcome | VAS | DDS | NRS | VAS | VAS |
| Follow up | 5 days | 2 weeks | 5-6 hours | ||
| Design | parallel | cross-over | |||
| Statistics | Mann- Whitney |
Wilcoxon Rank Sum |
General and linear mixed
models |
||
We summarize the five included randomized controlled clinical trials on inhaled cannabis for chronic neuropathic pain. The etiology of chronic neuropathic pain varied (including traumatic, central, diabetic and HIV-related). Study authors employed several patient reported pain outcome instruments: VAS (Visual Analogue Scale); NRS (Numerical Rating Scale); DDS (Descriptor Differential Scale).