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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Eur J Cancer. 2015 Nov 19;51(18):2792–2799. doi: 10.1016/j.ejca.2015.08.022

Figure 1.

Figure 1

(A) Number of identified resistance mechanisms per progression sample (B) Spectrum of resistance mechanisms in samples with only one identified alteration (C) Spectrum of resistance mechanisms in samples with >1 identified alteration co-occurring in the same sample

Legend: Green: mutation; Red: amplification; Blue: deletion; ^Distinct NRAS mutations identified in different samples