Table 1.
Patient and tumor characteristics for patients with negative findings at 3-month cystoscopy and available 6-week FISH results
| Total | Negative FISH Results | Positive FISH Results | p-value | |
|---|---|---|---|---|
| No. of patients | 95 | 58 | 37 | |
| Age: mean (±SD) | 66 ± 11.1 | 65 ± 12.2 | 66 ± 9.2 | 0.544 |
| Sex | ||||
| Female | 19 (20%) | 9 (16%) | 10 (27%) | 0.171 |
| Male | 76 (80%) | 49 (84%) | 27 (73%) | |
| Smoker (past or present) | 65 (68%) | 42 (72%) | 13 (35%) | 0.376 |
| Grade | ||||
| Low | 9 (10%) | 8 (14%) | 1 (3%) | 0.086 |
| High | 86 (90%) | 50 (86%) | 36 (97%) | |
| T Stage | ||||
| cTa | 38 (40%) | 24 (41%) | 14 (38%) | 0.948 |
| cT1 | 50 (53%) | 30 (52%) | 20 (54%) | |
| cTis | 7 (7%) | 4 (7%) | 3 (8%) | |
| Concurrent CIS | 48 (51%) | 21 (36%) | 27 (73%) | <0.001 |
| Prior Recurrence | ||||
| No | 16 (17%) | 10 (17%) | 6 (16%) | 0.914 |
| Single recurrence | 43 (45%) | 27 (47%) | 16 (43%) | |
| Multiple recurrence | 36 (38%) | 21 (36%) | 15 (41%) | |
| Recurrence | 23 (24%) | 6 (10%) | 17 (46%) | <0.001 |
| Progression | 17 (18%) | 5 (9%) | 12 (32%) | 0.005 |
| Radical cystectomy | 14 (15%) | 5 (9%) | 9 (24%) | 0.043 |
| Death | 6 (6%) | 3 (5%) | 3 (8%) | 0.677 |
| Cancer-specific death | 4 (4%) | 2 (3%) | 2 (5%) | 0.999 |
Of 100 patients in the entire cohort, 95 had 6-week FISH results sufficient for analysis; 2 had equivocal results.