Table 1.
Cell Line | Mutations | Subtypea |
---|---|---|
MDA-MB-468 | PTEN p.V85_splice | Basal |
HCC1937 | PTEN del/del | Basal |
MCF-7 | PIK3CA E545K | Luminal |
BT-483 | PIK3CA E542K | Luminal |
T-47D | PIK3CA H1047R | Luminal |
MDA-MB-453 | PIK3CA H1047R (PTENb) | Luminal |
Hs578T | HRAS G12D | Basal |
MDA-MB-134-VI | KRAS G12R | Luminal |
Subtype is based on the gene expression signature published by Neve et al.6
PTEN mutation with undefined effect.