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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Cytokine. 2015 Nov 3;77:63–71. doi: 10.1016/j.cyto.2015.10.007

Table 6.

Tables 6A and B. Multiple regression models based on clinical parameters of disease severity identified in our previous study[22] using the least squared method.

Table 6C reports the Pearson’s r, adjusted r2 and p-ANOVA values for the data in Tables 6A and B.

Tables 6A
P/F ratio day 8
vs placebo D0, n=7 Coefficients SE p
Intercept 227 14.7 ≤0.000
FGF-2 −2.480 0.266 0.001
IL-7 11.4 1.910 0.004
vs placebo D7, n=5 Coefficients SE P
none
vs GC, n=9 Coefficients SE p
Intercept 119.044 41.933 0.025
WBC 5.386 5.956 0.396
Neutrophils 1.855 1.283 0.192
vs GC D7, n=7 Coefficients SE p
Intercept 456.169 23.987 ≤0.000
fractalkine −1.256 0.360 0.025
lymphocytes −2.419 0.646 0.020
PP day 2
vs placebo D0, n=18 Coefficients SE P
none
vs placebo D7, n=17 Coefficients SE P
Intercept 7.743 0.497 0.001
IL-10 0.115 0.006 ≤0.000
IL-12P70 −0.005 0.001 0.002
lymphocytes 0.071 0.004 ≤0.000
vs GC D0, n=15 Coefficients SE p
none
vs GC D7, n=8 Coefficients SE p
none
PaCO2 day 2
vs placebo D0, n=18 Coefficients SE P
none
vs placebo D7, n=17 Coefficients SE P
none
vs GC D0, n=15 Coefficients SE P
none
vs GC D7, n=8 Coefficients SE P
none
Tables 6B
Racemic epinephrine
vs placebo D0, n=17 Coefficients SE P
Intercept 0.755 0.216 0.004
MCP-1 ≤0.000 ≤0.000 0.016
lymphocytes 0.015 0.005 0.012
vs placebo D7, n=7 Coefficients SE P
Intercept 0.175 0.154 0.318
IFN-y 0.083 0.021 0.017
lymphocytes 0.017 0.006 0.039
vs GC D0, n=16 Coefficients SE p
none
vs GC D7, n=8 Coefficients SE p
none
O2 at discharge
vs placebo D0, n=17 Coefficients SE P
Intercept 2.017 0.008 ≤0.000
Flt-3L −0.002 ≤0.000 0.001
IL-10 ≤0.000 ≤0.000 0.001
IL-1RA ≤0.000 ≤0.000 ≤0.000
IL-6 ≤0.000 ≤0.000 0.004
MCP-1 ≤0.000 ≤0.000 0.013
MIP-1β 0.001 ≤0.000 ≤0.000
lymphocytes ≤0.000 ≤0.000 0.007
vs placebo D7, n=7 Coefficients SE P
Intercept 1.933 0.004 ≤0.000
eotaxin ≤0.000 ≤0.000 0.010
Fit-3L ≤0.000 ≤0.000 0.003
IL-10 −0.002 ≤0.000 0.008
IL-15 0.027 0.001 0.001
vs GC D0, n=16 Coefficients SE P
none
vs GC D7, n=6 Coefficients SE P
Intercept 3.711 0.157 ≤0.000
PTT −0.009 0.005 0.168
Table 6C
P/F ratio day 8 r Adjusted r2 p-ANOVA
vs placebo day 0 0.097 0.935 0.002
vs GC day 0 0.833 0.694 0.016
vs placebo day 7 0.978 0.932 0.002
vs GC day 7 0.978 0.932 0.002
PP day 2
vs placebo day 0 none - -
vs GC day 0 none - -
vs placebo day 7 1 1 ≤0.000
vs GC day 7 none - -
PaCO2 day 2
vs placebo day 0 none - -
vs GC day 0 none - -
vs placebo day 7 none - -
vs GC day 7 none - -
Racemic epinephrine
vs placebo day 0 0.809 0.604 0.001
vs GC day 0 none - -
vs placebo day 7 0.978 0.936 0.002
vs GC day 7 none - -
O2 at transfer
vs placebo day 0 1 1 ≤0.000
vs GC day 0 none - -
vs placebo day 7 1 1 ≤0.000
vs GC day 7 0.991 0.970 0.002