Fig. 5.

State 3 respiration rates in brain mitochondria. A: state 3 respiration rates at midarousal from hibernation in brain mitochondria from animals treated with luzindole (gray) or vehicle (black). Luzindole-treated animals had significantly lower respiration rates with succinate (SUC; *P = 0.019, t-test). G/M, glutamate/malate. B: state 3 respiration rates during summer in brain mitochondria from animals treated with luzindole (gray) or vehicle (black). Vehicle-treated animals had significantly higher respiration rates with glycerol-3-phosphate (G3P; *P = 0.0496, t-test). Number of animals (n) for each group is listed at the bottom of the respective bar. Error bars represent means ± SE.