Fig. 1.

Glucose metabolic rates measured in late-gestation control (CON) and intrauterine growth-restricted (IUGR) fetal sheep during basal and hyperinsulinemic clamp (insulin) periods. Glucose utilization rate was measured with U-[¹⁴C]glucose tracer. Glucose oxidation rate was determined based on ¹⁴CO₂ measurements. Glucose oxidation fraction represents the fraction of glucose utilized that was oxidized. Values expressed as means ± SE are shown for CON (n = 4) and IUGR (n = 8) fetuses studied during basal (white bars) and insulin-clamp periods (black bars). Significant effects from two-way ANOVA are indicated.