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Effect of FSS on NADPH oxidase 4 (Nox4) gene expression in HCAEC and HCASMC. A: in HCAEC, high FSS significantly increased Nox4 mRNA compared with static control at 4 h after exposure, while normal FSS had no significant effect on Nox4 mRNA (n = 5). *P < 0.01. B: high FSS increased Nox4 mRNA only at 24 h after exposure in HCASMC (n = 5). *P < 0.05.
