Fig. 3.
NAC desensitizes the myofilament to Ca2+ in NTg and Tm-E180G myofilaments. A: comparison of pCa-tension relationships of NTg, NTg NAC, Tm-E180G, and Tm-E180G NAC mice. B: comparison of Ca2+ sensitivity of ATPase rates among NTg, NTg NAC, Tm-E180G, and Tm-E180G NAC mice. Data are represented as means ± SE; n = 6–7 fibers, 3–5 hearts, per group.