Table 4.
Significant risk factors affecting complications from univariate analysis.
| Complication | Significant variables | p value |
|---|---|---|
| Extramedullary hematopoiesis | Gender (female) | 0.050 |
| Thalassemia type (beta) | 0.031 | |
| Hemoglobin < 8 g/dL | 0.003 | |
| Platelets > 400,000 per cumm. | 0.025 | |
| Maximum ferritin > 800 ng/mL | 0.004 | |
| Splenectomy | 0.019 | |
| Iron chelation | 0.001 | |
|
| ||
| Pulmonary hypertension | None | — |
|
| ||
| Heart failure | Splenectomy | 0.035 |
|
| ||
| Cholelithiasis | None | — |
|
| ||
| Abnormal LFT (ALT >50 U/L) | Iron chelation | 0.007 |
| Maximum ferritin > 800 ng/mL | 0.041 | |
| HCV infection∗ | 0.143 | |
|
| ||
| Osteoporosis | Gender (female) | 0.006 |
| Age > 40 years | 0.003 | |
|
| ||
| Abnormal plasma glucose | None | — |
|
| ||
| Hypothyroidism | None | — |
|
| ||
| Hypogonadism | Splenectomy | 0.016 |
∗ p value is not significant.