Table 1.

Effect of OTH on ear edema induced by single application of croton oil.

Group	Concentration (mg/mL)	Edema (mg)	Inhibition (%)
Negative control	—	11.20 ± 0.39	—
Dexamethasone	4	1.43 ± 0.46∗∗∗	87.5%
OTH	Pure	5.71 ± 0.68∗∗∗	49.1%
OTH	100	8.37 ± 0.71∗	25.0%
OTH	200	11.00 ± 0.73	1.78%
OTH	400	9.51 ± 0.74	15.0%

Values expressed as mean ± SEM (^∗ p < 0.05; ^∗∗∗ p < 0.001 versus control); (ANOVA and Student-Newman-Keuls test).