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Perivascular niche and multipotency of mesenchymal stem cells (MSC). Mesenchymal stem cells reside in perivascular niches where they undergo self-renewal and maintain the surrounding cells/tissue. Under specific signaling conditions, MSC can undergo differentiation into the osteoblastic (osteocytic), endothelial, chondrocytic, adipocytic, odontoblastic, and neural lineages.
