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. 2015 Dec 2;9:466. doi: 10.3389/fncel.2015.00466

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Copyright © 2015 Alsharafi, Xiao, Abuhamed, Bi and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) miR-187 relative dynamic expression in the three phases of TLE development in a rat model. qPCR results showed significant downregulation occurred in the latent and chronic phases compared to controls, with lowest expression in the chronic phase. In the acute phase, no significant deregulation was observed. (B) Relative expression of miR-187 in the hippocampal tissues obtained from patients with TLE and normal controls. qPCR results showed significant downregulation occurred in the TLE patients compared to normal controls (n = 5/group; ^*p < 0.05). HC, human control; HE, human epilepsy.