Table 3. The Mean Blood Pressure (MBP) and Heart Rate (HR) after Administration of Reversal Agents.
Time after reverse (min) | Group | P value | ||||
---|---|---|---|---|---|---|
S2 | S1 | SN | N | |||
MBP (mmHg) | 0 | 77.9 ± 12.7* | 74.6 ± 11.6 | 70.1 ± 10.3† | 76.2 ± 11.4* | 0.049 |
2 | 77.8 ± 14.2 | 77.8 ± 13.3 | 74.5 ± 12.6 | 77.8 ± 14.6 | 0.641 | |
5 | 79.1 ± 13.7* | 83.3 ± 15.6*,† | 70.9 ± 10.4 | 72.4 ± 13.9 | 0.002 | |
10 | 88.2 ± 16.0† | 86.7 ± 17.6† | 80.1 ± 14.6 | 75.3 ± 13.1 | 0.007 | |
HR (bpm) | 0 | 75.4 ± 11.8 | 73.0 ± 12.2 | 71.3 ± 12.0 | 71.1 ± 13.2 | 0.354 |
2 | 70.5 ± 11.3 | 71.2 ± 11.1 | 73.3 ± 11.3 | 68.6 ± 12.3 | 0.251 | |
5 | 71.3 ± 12.7*,‡ | 70.1 ± 12.7*,‡ | 61.5 ± 10.9 | 58.1 ± 11.7 | < 0.001 | |
10 | 78.2 ± 12.7*,‡ | 73.1 ± 12.4‡ | 69.2 ± 17.8† | 56.5 ± 10.3* | < 0.001 |
Values are expressed as mean ± standard deviation. Group S2: sugammadex 2 mg/kg, Group S1: sugammadex 1 mg/kg, Group SN: sugammadex 1 mg/kg + neostigmine 50 µg/kg + glycopyrrolate 10 µg/kg, Group N: neostigmine 50 µg/kg + glycopyrrolate 10 µg/kg (*P < 0.05 when compared with group SN, †P < 0.05 when compared with group N, ‡P < 0.001 when compared with group N).