Table 1.
Demographic and Clinical Characteristics of Study Cohort (n = 273)
| Variable | Pheochromocytoma Group (n = 84) | Non-Pheochromocytoma Group (n = 189) |
|---|---|---|
| Value n (%) or n (Range) | Value n (%) or n (Range) | |
| Median age of VHL diagnosis | 27.6 (5–68) | 25.6 (4.7–63.5) |
| Median age of pheochromocytoma diagnosis | 28 (5.5–68) | NA |
| Male:female | 46:38 | 80:109 |
| Pediatric patients (<19 years) | 21 | 44 |
| Median age of pheochromocytoma diagnosis in pediatric group | 12.4 (5.5–18.7) | NA |
| Follow-up duration (weeks) | 116.6 (0.1–613.2) | 203.8 (0.7–912) |
| Location of tumor at first surgery | ||
| Left adrenal (%) | 35 (45.2) | NA |
| Right adrenal (%) | 27 (32.1) | NA |
| Bilateral adrenal (%) | 13 (15.5) | NA |
| Retroperitoneal (%) | 4 (4.8) | NA |
| Periadrenal (%) | 1 (1) | NA |
| Unknown (%) | 3 (3.6) | NA |
| Pathology of tumor at first surgery | ||
| Pheochromocytoma (%) | 81 (96.4) | NA |
| Missing (%) | 3 (3.6) | NA |
| Median tumor size at first surgerya | 2.7 cm (0.6–18) | NA |
| Second surgery for primary tumor (n) | 17 | NA |
| Recurrences (n) | 9 | NA |
Abbreviation: NA, not applicable.
a
Including additional tumors that were identified at the time of partial adrenalectomy.