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. 2015 Dec 2;5:17338. doi: 10.1038/srep17338

Figure 1. NT4X antibody binds specifically to AβpE3-42 and Aβ4-42 peptides.

Figure 1

Sensorgram profiles generated by binding studies using the Biacore T200 showing the association and dissociation binding kinetics of the NT4X antibody to freshly prepared AβpE3-42 (a), Aβ4-42 (b) and Aβ1-42 (c) peptides. NT4X binds to AβpE3-42 and Aβ4-42 but does not bind to Aβ1-42. The heterogeneous nature of the Aβ peptides limits this application in obtaining accurate kinetic data. However, the theoretical fit of binding of AβpE3-42 (d) and Aβ4-42 (e) peptides to the NT4X antibody and their kinetics of binding (f) is also shown. Abbreviations: RU: response units; Kon: association rate, Koff: dissociation rate; KD: equilibrium constant.