Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 2;5:17338. doi: 10.1038/srep17338

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A,B) Working memory deficits were induced by intraventricular injection of Aβ_4-42 as the mice performing at chance level (dashed line). Both treatment with (a) full-length antibody and (b) Fab fragment rescued memory deficits in a dose-dependent manner. Mice treated with the vehicle control and the vehicle in combination with full-length or Fab fragment of NT4X respectively demonstrated normal working memory performance. One-way analysis of variance (ANOVA) followed by Bonferroni multiple comparisons; n = 6–8 per group; **p < 0.01; *p < 0.05; data presented as mean ± S.E.M.