Table 2.

Model Parameters Compared With Published Values.

Model parameter	Parameter name	Description	Published value	Model fit	Percentage difference	Reference
1	F01	Non-insulin-mediated glucose uptake	0.010	0.0104	7.50	16
2	Vg	Distribution volume—glucose	0.160	0.1797	12.30	16
3	K12	Rate constant—glucose compartments	0.066	0.0793	20.17	16
4	Ag	Proportion of absorbed carbs	0.800	0.8121	1.51	16
5	tmaxG	Time to max carb absorption rate	40.000	48.8385	22.10	16
6	EGP0	Endogenous glucose production base	0.016	0.0158	−1.67	16
7	K	Proportion of insulin in slow compartment	0.670	0.7958	18.77	18
8	k1	Rate constant—slow insulin compartment	0.011	0.0113	1.08	18
9	k2	Rate constant—fast insulin compartment	0.021	0.0197	−6.21	18
10	k3	Elimination rate constant—plasma insulin	0.138	0.1735	25.72	18
11	VmaxLD	Max velocity of local degradation—insulin	1.930	2.9639	53.57	18
12	kMLD	Michaelis constant—insulin	62.600	47.5305	−24.07	16
13	VI	Distribution volume—insulin	0.120	0.1443	20.28	16
14	ka1	Removal of effect—glucose distribution	0.006	0.0070	16.37	16
15	ka2	Removal of effect—glucose disposal	0.060	0.0331	−44.91	16
16	ka3	Removal of effect—EGP suppression	0.030	0.0308	2.59	16
17	SfIT	Sensitivity—glucose distribution	0.005	0.0046	−9.51	16
18	SfID	Sensitivity—glucose disposal	0.001	0.0006	−23.72	16
19	SfIE	Sensitivity—EGP suppression	0.052	0.0384	−26.13	16